Overview A Research Scientist position is available in the laboratory of Dr. Xiaoting Zhang in the Department of Cancer Biology at the University of Cincinnati College of Medicine, to study transcriptional and epigenetic gene regulation in breast cancer metastasis and therapeutic resistance. The Zhang laboratory focuses on elucidating the role and molecular mechanisms of gene- and tissue-specific transcriptional cofactors, small RNAs and liquid-liquid phase separation (LLPS) in the above processes. We are using a combination of biochemical, molecular, genomic, and mouse genetic approaches and are developing RNA-based nano-therapeutics to target these cofactors and small RNAs to overcome therapeutic resistance of human breast cancer. Responsibilities Independently design and conduct the research required by the faculty supervisor to a high standard and in accordance with all institutional and federal regulations. Prepare research results, write manuscripts independently, and engage in the dissemination and presentation of the results of the research. Support the development of proposals and write research-related funding and grants. Participate in appropriate training and professional development opportunities. May provide direct and/or indirect supervision to exempt and non-exempt staff and perform additional related duties as needed. Required Education PhD and/or MD required. Required Experience Additional related work experience may be required depending on field or discipline. Additional Qualifications Considered Prior experience and in-depth knowledge in cancer biology, molecular cellular biology, protein biochemistry, small RNAs, or LLPS is ideal. Physical Requirements / Work Environment Sitting – Continuously Repetitive hand motion (typing) – Often Hearing, listening – Often Talking – Often Standing – Often Walking – Often Bending – Seldom Stooping – Seldom Climbing stairs/ladders – Seldom Kneeling, squatting – Seldom Crouching – Seldom Crawling – Seldom Reaching overhead – Seldom Lifting – up to 20 pounds – Seldom Lifting – up to 50 pounds – Seldom Lifting – over 50 pounds – Seldom Compensation and Benefits UC offers an exceptional benefits package designed to support well-being, financial security, and work-life balance. Highlights include: Comprehensive Tuition Remission for you and eligible dependents Robust Retirement Plans (OPERS, STRS) or Alternative Retirement Plan; UC may contribute 14–18% of salary based on position Work-life balance with generous time-off, including vacation and sick time, 11 paid holidays, end-of-year paid time off (Winter Season Days), and 6 weeks of paid parental leave Competitive salary based on experience; comprehensive health coverage; flexible spending accounts and wellness programs; professional development and mentorship opportunities To learn more about why UC is a great place to work, please visit the careers page at UC is an Equal Opportunity Employer. E-Verify participation and Form I-9 requirements apply for employment eligibility.
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